Description

Kisspeptin-10

Kisspeptin-10 is a synthetic peptide corresponding to the biologically active C-terminal region of the naturally occurring kisspeptin peptide family. It is studied experimentally in relation to the kisspeptin receptor (KISS1R/GPR54) and associated hypothalamic and reproductive endocrine signalling pathways.

Kisspeptin signalling is an established area of scientific interest because of its involvement in the regulation of gonadotropin-releasing hormone (GnRH) and the downstream hypothalamic-pituitary-gonadal (HPG) axis.

Benchmark Peptides supplies Kisspeptin-10 as a research material for laboratory and analytical use only. This product is not supplied or intended for human or veterinary use.

Product Specifications

• Product: Kisspeptin-10
• Catalogue Reference: KS10
• Quantity: 5 mg
• Physical Form: Lyophilised material
• Appearance: White to off-white
• Grade: Research grade
• Batch: See current batch information
• Analytical Documentation: See current Certificate of Analysis

Research Information

Kisspeptin-10 is a synthetic decapeptide investigated primarily in relation to KISS1R receptor signalling and its role within neuroendocrine and reproductive endocrine pathways.

KISS1R, historically referred to as GPR54, is a G-protein-coupled receptor. Interaction between endogenous kisspeptins and this receptor forms an important signalling pathway associated with the regulation of hypothalamic GnRH activity.

Scientific research involving Kisspeptin-10 and its associated pathways includes investigation of:

• KISS1R/GPR54 receptor signalling
• Kisspeptin-receptor interactions
• Gonadotropin-releasing hormone (GnRH) signalling
• Hypothalamic-pituitary-gonadal axis physiology
• Luteinising hormone (LH) and follicle-stimulating hormone (FSH) signalling
• Neuroendocrine regulation
• Reproductive endocrine signalling
• Pubertal and reproductive physiology

Kisspeptin-10 therefore provides a laboratory research model for investigating peptide-receptor interactions and signalling mechanisms associated with the reproductive endocrine system.

Information provided by Benchmark Peptides is intended solely to identify and characterise the research material supplied. It should not be interpreted as medical information, treatment guidance or a recommendation for use.

Batch & Quality Information

Batch-specific analytical information is provided through the Certificate of Analysis available for this product.

Where available, the Certificate of Analysis provides information including:

• Batch identification
• Analytical identity
• Analytical purity
• Testing methodology
• Laboratory information
• Test date and associated analytical data

Analytical results relate specifically to the identified batch and should not be interpreted as establishing suitability for any particular application.

Storage & Laboratory Handling

Store the sealed research material according to the conditions specified in the applicable product or batch documentation.

For longer-term laboratory storage, protect the material from excessive heat, moisture and direct light.

Where the material is prepared in solution for legitimate analytical or laboratory work, appropriate preparation, handling and storage conditions should be determined by the researcher’s validated laboratory protocol.

Package Contents

• 1 × Kisspeptin-10 research vial
• 5 mg total peptide content
• Tamper-evident closure
• Batch identification

Product Category

Endocrine Research

This material is categorised according to its use in experimental research involving KISS1R, GnRH and hypothalamic-pituitary-gonadal endocrine signalling pathways.

Important Notice

FOR RESEARCH USE ONLY

Supplied exclusively as a laboratory research material.

NOT FOR HUMAN OR VETERINARY USE.

Not supplied for administration, diagnosis, treatment, cure or prevention of any disease.

Researchers are responsible for ensuring that acquisition, possession, handling and use comply with all applicable laws, regulations and institutional requirements.