Description

AICAR 50 mg

AICAR (5-Aminoimidazole-4-carboxamide ribonucleoside) is a synthetic research compound investigated experimentally in relation to AMP-activated protein kinase (AMPK) and associated cellular metabolic signalling pathways.

AICAR is studied in biochemical and molecular research involving intracellular nucleotide metabolism, cellular energy sensing and enzyme-associated signalling mechanisms.

Benchmark Peptides supplies AICAR as a research material for laboratory and analytical use only. This product is not supplied or intended for human or veterinary use.

Product Specifications

• Product: AICAR
• Chemical Name: 5-Aminoimidazole-4-carboxamide ribonucleoside
• Catalogue Reference: AR50
• Quantity: 50 mg
• Physical Form: See current batch documentation
• Appearance: See current batch documentation
• Grade: Research grade
• Batch: See current batch information
• Analytical Documentation: See current Certificate of Analysis, where available

Research Information

AICAR is a synthetic nucleoside analogue investigated in relation to cellular energy regulation and AMP-activated protein kinase (AMPK) signalling.

AMPK is an intracellular enzyme complex involved in cellular energy sensing and associated biochemical regulatory pathways.

In experimental cellular systems, AICAR can undergo intracellular phosphorylation to form ZMP, a nucleotide analogue associated with AMP-sensitive biochemical signalling mechanisms.

Scientific research involving AICAR and its associated pathways includes investigation of:

• AMP-activated protein kinase (AMPK) signalling
• Cellular energy-sensing mechanisms
• Intracellular nucleotide metabolism
• Enzyme-associated metabolic signalling
• Mitochondrial cellular biology
• Glucose-associated biochemical pathways
• Lipid-associated metabolic signalling
• Cellular responses to changes in energy availability
• Nucleotide-dependent regulatory mechanisms

Experimental research involving AICAR includes investigations of AMPK-associated and AMPK-independent biochemical mechanisms.

The available scientific literature includes in-vitro and preclinical investigations. Findings from these experimental systems should not be interpreted as establishing clinical outcomes or suitability for any particular application.

Information provided by Benchmark Peptides is intended solely to identify and characterise the research material supplied. It should not be interpreted as medical information, treatment guidance or a recommendation for use.

Batch & Quality Information

Batch-specific analytical information is provided through the Certificate of Analysis where available for this product.

Where available, the Certificate of Analysis provides information including:

• Batch identification
• Analytical identity
• Analytical purity
• Testing methodology
• Laboratory information
• Test date and associated analytical data

Analytical results relate specifically to the identified batch and should not be interpreted as establishing suitability for any particular application.

Storage & Laboratory Handling

Store the sealed research material according to the conditions specified in the applicable product or batch documentation.

For longer-term laboratory storage, protect the material from excessive heat, moisture and direct light, subject to the manufacturer’s documented storage requirements.

Where the material is prepared in solution for legitimate analytical or laboratory work, appropriate preparation, handling and storage conditions should be determined by the researcher’s validated laboratory protocol.

Package Contents

• 1 × AICAR research vial
• 50 mg nominal compound content
• Sealed closure
• Batch identification

Product Category

Cellular Metabolism

This material is categorised according to its relevance to experimental research involving AMPK signalling, intracellular nucleotide metabolism and cellular energy-regulation pathways.

Important Notice

FOR RESEARCH USE ONLY

Supplied exclusively as a laboratory research material.

NOT FOR HUMAN OR VETERINARY USE.

Not supplied for administration, diagnosis, treatment, cure or prevention of any disease.

Researchers are responsible for ensuring that acquisition, possession, handling and use comply with all applicable laws, regulations and institutional requirements.